Coordinated by Maria Sibilia, Univ.-Prof. Mag. Dr., Head
Main research area:
Investigation of the basic mechanisms leading to tumor development with particular emphasis on molecular cancer epidemiology, cancer cell signaling and therapy, mutagenesis, tumor-stroma interactions and the impact of inflammation on tumorigenesis.
Coordinated by Walter Berger, Univ.-Prof. Mag. Dr.
Main research area:
Development and evaluation of novel anticancer compounds and/or therapy targets based on the precise elucidation of molecular factors underlying cancer development and progression. Elaboration of strategies to avoid therapy resistance against classical chemotherapy and novel targeted anticancer compounds.
Coordinated by Gergely Szakacs, Univ.-Prof. PhD
Main research area:
Characterization of the toxicologic and carcinogenic potential of chemicals. Investigation of the complex cellular pathways by which cancer risk factors affect the multistep evolution of cancer. Elucidation of the molecular basis of therapy resistance.
Coordinated by Wolfgang Mikulits, Ao.Univ.-Prof. Mag. Dr.
Main research area:
Identification and characterization of molecular mechanisms which promote tumor cells to invade into the surrounding tissue and into the circulation to form metastases. Examination of molecular mechanisms which educate cells of the tumor microenvironment such as cancer-associated fibroblasts and immune cells to facilitate metastatic colonization.