Abk�rzung zur Hauptnavigation Abk�rzung zu den Newsmeldungen Abk�rzung zu den Topstories  
English Version English Version
  MedUni Wien  trenner  Intranet  trenner  MedUni Wien - Shop  trenner  Universitätsbibliothek  trenner  Universitätsklinikum AKH Wien  trenner
 
Krebsforschung.png
 
 
 
Hauptnavigation
  • Home
  • Mission Statement
    • Chronik
    • 50 Jahre Institut für Krebsforschung
    • Imagevideo: Institut für Krebsforschung
  • Forschung
    • Forschungsschwerpunkte
    • Forschungsgruppen
    • Wissenschaftliche Services - Core Facilities
  • Lehre
    • Vorlesungen und Seminare des Institutes
    • Universitätslehrgang Toxikologie für Postgraduierte
    • PhD Program Inflammation and Immunity
    • PhD Program IPPTO Translational Oncology
    • PhD Programm Malignant Diseases
    • PhD Programm Clinical and Experimental Oncology
  • Kontakt
    • Kontakt
    • Lageplan
 
Forschung / Forschungsschwerpunkte / Sicherheit chemischer Substanzen und Krebsprävention / Wolfgang Huber
 
Subnavigation
  • Forschungsschwerpunkte
    • Zelluläre und molekulare Tumorbiologie
    • Angewandte und experimentelle Onkologie
    • Sicherheit chemischer Substanzen und Krebsprävention
      • Gergely Szakacs
      • Bettina Grasl-Kraupp
      • Wolfgang Huber
        • Research Projects
        • Group Members
      • Siegfried Knasmüller
      • Teaching
    • Progression und Metastasierung von Tumoren
  • Forschungsgruppen
  • Wissenschaftliche Services - Core Facilities


Inhaltsbereich
Wolfgang Huber, Ao.Univ.-Prof. Dr.

 

Wolfgang Huber, Ao.Univ.-Prof. Dr.
Gruppenleiter
E-Mail: wolfgang.huber [at] meduniwien [dot] ac [dot] at
Phone:  +43 (0)1 40160 - 57613
Fax: +43 (0)1 40160 - 957500

Research Focus

Chemical substances are not only known as relevant carcinogens but may also play an important role in the prevention of cancer. Our reseach deals with mechanisms that are involved in such chemoprevention, which is e.g. achieved by certain coffee components. Our research targets include beneficial effects on carcinogen metabolism, by which carcinogens may be both activated and detoxified, as well as antioxidant effects, since oxidative stress has been found to be crucial during several stages of the carcinogenic process, and stimulation of DNA-repair.

Group Members

Selected Publications:

Proinflammatory mesenchymal effects of the non-genotoxic hepatocarcinogen phenobarbital: a novel mechanism of antiapoptosis and tumor promotion.
Riegler T, Nejabat M, Eichner J, Stiebellehner M, Subosits S, Bilban M, Zell A, Huber WW, Schulte-Hermann R, Grasl-Kraupp B.; Carcinogenesis. 2015 Sep 16

Protective effects of coffee against induction of DNA damage and pre-neoplastic foci by aflatoxin B₁.
Ferk F, Huber WW, Grasl-Kraupp B, Speer K, Buchmann S, Bohacek R, Mišík M, Edelbauer L, Knasmüller S.; Mol Nutr Food Res. 2014 Feb; 58(2):229-38

Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).
Ferk F, Huber WW, Filipic M, Bichler J, Haslinger E, Misík M, Nersesyan A, Grasl-Kraupp B, Zegura B, Knasmüller S.; Mutat Res. 2010 Sep 10; 691(1-2):17-22

Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
Huber WW
, Rossmanith W, Grusch M, Haslinger E, Prustomersky S, Peter-Vörösmarty B, Parzefall W, Scharf G, Schulte-Hermann R.; Food Chem Toxicol. 2008 Apr; 46(4):1230-8

Thiols and the chemoprevention of cancer.
Huber WW
, Parzefall W.; Curr Opin Pharmacol. 2007 Aug; 7(4):404-9

 

All Publications:

PubMed Database  

 
Drucken
 
 
© MedUni Wien | Impressum | Nutzungsbedingungen | Datenschutzerklärung | Barrierefreiheit | Kontakt