Calcium signals in B-RAF mutated cancer cells

Together with the groups of Agnes Enyedi and Enikö Kallay we are investigating the differential regulation of calcium signals between cancer cells with mutated and wild-type B-RAF in melanoma and colorectal cancer cells. These differences could have an important impact on tumor cell aggressiveness and therapy resistance.

Students: Luca Hegedüs, Matthias Wolf

Collaborations: Agnes Enyedi (Semmelweiss University, Budapest, Hungary), Enikö Kallay (Department of Pathophysiology and Allergy Research, Medical University of Vienna).

Financial support: FWF/OTKA

Research Focus: Development of Experimental Cancer Therapies