The publications listed represent only a selection of the publications published by the employees of the center. You will find further publications on the pages of the research groups.
Insertion of (Bioactive) Equatorial Ligands into Platinum(IV) Complexes
Alexander Kastner, Hemma Schueffl, Patrick A. Yassemipour, Bernhard K. Keppler, Petra Heffeter#,Christian R. Kowol#
# Corresponding author
Angewandte Chemie: https://doi.org/10.1002/anie.202311468
Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege
Karoline Strobl, Joerg Klufa, Regina Jin, Lena Artner-Gent, Dana Krauss, Philipp Novoszel, Johanna Strobl, Georg Stary, Igor Vujic, Johannes Griss, Martin Holcmann, Matthias Farlik, Bernhard Homey, Maria Sibilia, Thomas Bauer.
bioRxiv - The Preprint Server for Biology https://www.biorxiv.org/content/10.1101/2023.10.11.561653v1
Targeting YB-1 via entinostat enhances cisplatin sensitivity of pleural mesothelioma in vitro and in vivo.
Schelch K, Emminger D, Zitta B, Johnson TG, Kopatz V, Eder S, Ries A, Stefanelli A, Heffeter P, Hoda MA, Hoetzenecker K, Dome B, Berger W, Reid G, Grusch M.
Cancer Lett. 2023 Sep 18:216395. doi: 10.1016/j.canlet.2023.216395
Effective targeting of breast cancer by the inhibition of P-glycoprotein mediated removal of toxic lipid peroxidation byproducts from drug tolerant persister cells
Kornélia Szebényi, András Füredi, Eszter Bajtai, Sai Nagender Sama, Agnes Csiszar, Balázs Gombos, Pál Szabó, Michael Grusch, Gergely Szakács.
Drug Resistance Updates, (2023), doi:https://doi.org/10.1016/j.drup.2023.101007
Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo
Paul Strasser, Bianca Montsch, Silvia Weiss, Haider Sami, Christoph Kugler, Sonja Hager, Hemma Schueffl, Robert Mader, Oliver Brüggemann, Christian R Kowol, Manfred Ogris, Petra Heffeter, Ian Teasdale
Small. 2023 Feb 26;e2300767.vdoi: 10.1002/smll.202300767.
Mesothelioma‑associated fibroblasts enhance proliferation and migration of pleural mesothelioma cells via c‑Met/PI3K and WNT signaling but do not protect against cisplatin
Alexander Ries, Daniela Flehberger, Astrid Slany, Christine Pirker, Johanna C. Mader, Thomas Mohr, Karin Schelch, Katharina Sinn, Berta Mosleh, Mir Alireza Hoda, Balazs Dome, Helmut Dolznig, Georg Krupitza, Leonhard Müllauer, Christopher Gerner, Walter Berger & Michael Grusch
J Exp Clin Cancer Res. 2023 Jan 23;42(1):27. doi: 10.1186/s13046-022-02582-0.
In-depth proteomic analysis reveals unique subtype-specific signatures in human small-cell lung cancer
Beáta Szeitz, Zsolt Megyesfalvi, Nicole Woldmar, Zsuzsanna Valkó, Anna Schwendenwein, Nándor Bárány, Sándor Paku, Viktória László, Helga Kiss, Edina Bugyik, Christian Lang, Attila Marcell Szász, Luciana Pizzatti, Krisztina Bogos, Mir Alireza Hoda, Konrad Hoetzenecker, György Marko-Varga, Peter Horvatovich, Balázs Döme, Karin Schelch, Melinda Rezeli.
Clin Transl Med 2022 Sep;12(9):e1060.doi: 10.1002/ctm2.1060.
Molecular and Pharmacological Bladder Cancer Therapy Screening: Discovery of Clofarabine as a Highly Active Compound
Iris E Ertl, Ursula Lemberger, Dafina Ilijazi, Melanie R. Hassler, Andreas Bruchbacher, Robert Brettner, Hannah Kronabitter, Michael Gutmann, Petra Vician, Gerhard Zeitler, Anna Koren, Charles-Hugues Lardeau, Thomas Mohr, Andrea Haitel, Eva Compérat, André Oszwald, Gabriel Wasinger, Thomas Clozel, Olivier Elemento, Stefan Kubicek, Walter Berger, Shahrokh F Shariat.
Eur Urol 2022 Sep;82(3):261-270.doi: 10.1016/j.eururo.2022.03.009. Epub 2022 Apr 4.
The Anticancer Ruthenium Compound BOLD-100 Targets Glycolysis and Generates a Metabolic Vulnerability towards Glucose Deprivation
Baier D, Schoenhacker-Alte B, Rusz M, Pirker C, Mohr T, Mendrina T, Kirchhofer D, Meier-Menches SM, Hohenwallner K, Schaier M, Rampler E, Koellensperger G, Heffeter P, Keppler B, Berger W.
Pharmaceutics. 2022 Jan 20;14(2):238.doi: 10.3390/pharmaceutics14020238.
The AP-1 transcription factors c-Jun and JunB are essential for CD8α conventional dendritic cell identity
Philipp Novoszel #, Barbara Drobits #, Martin Holcmann, Cristiano De Sa Fernandes, Roland Tschismarov, Sophia Derdak, Thomas Decker, Erwin F Wagner, Maria Sibilia
Cell Death Differ 2021 Aug;28(8):2404-2420.doi: 10.1038/s41418-021-00765-4. Epub 2021 Mar 23.