Prognostic and predictive biomarkers in breast cancer
Tumor tissue contains important information about genetic and other molecular changes in the tumor that lead to cancer. This information can be decoded using modern molecular biological and biochemical methods and used for cancer research. The prerequisite for this is a tissue collection in which both tumor and normal tissue is stored and which enables a comparison of the laboratory results with the patient data. Thanks to its many years of clinical research work, the ABCSG (Austrian Breast and Colorectal Cancer Study Group) has a detailed collection of patient data and, therefore, provides an excellent basis for translational research projects.
The ABCSG is very successful in standardizing and continuously improving the treatment of breast and colon cancer in Austria. Sophisticated clinical studies, the trust of more than 20,000 participants and the maximum commitment of the 100 ABCSG centers made this possible. This success story has now placed the ABCSG in the top tier of European academic study groups.
In order to improve the treatment and prognosis of women with breast cancer, we examine the tumor tissue of cancer patients for genetic and morphological changes or for the activity of various proteins.